Future episodes in the CardioBites: Inflammation Series:
What is the Role of Systemic Inflammation in ASCVD and Heart Failure? Inflammation occurs in most forms of myocardial injury and plays a significant role in atherosclerotic cardiovascular disease (ASCVD) and both acute and chronic forms of heart failure. In this series, we examine the role of systemic inflammation in cardiovascular disease. Watch now
What is the Pathogensis of Inflammation As It Relates to Cardiovascular Disease? Inflammation is an important, under-recognized contributor to cardiovascular diseases ranging from atherosclerotic disease to heart failure. In this video, we explore the pathogenesis of inflammation as it relates to cardiovascular disease. Watch now
How does One Screen for/Diagnose Systemic Inflammation as It relates to Cardiovascular Disease?
Diuretics are essential in the care of patients with heart failure—but what happens when oral therapy isn’t enough and IV access isn’t feasible? In this quick, evidence-based video, we highlight the data behind subcutaneous furosemide, a novel outpatient option that may offer more flexibility in managing congestion. Watch now
What are The Current/Emerging Interventions for Systemic Inflammation in CVD, and The Impact on Practice?
Systemic inflammation causes microvascular dysfunction and promotes maladaptive cardiac remodeling, which in turn can contribute to the development of heart failure, both with preserved ejection fraction and reduced ejection fraction. Inflammation also activates the renin-angiotensin-aldosterone system, which then causes vasoconstriction and fluid retention while increasing circulating cytokines such as IL-6 and tumor necrosis factor-alpha, which can promote fibrosis and hypertrophy of cardiac muscle.
In this video, we explore the current interventions and interventions in development to address systemic inflammation. Specifically, we look at the data, which shows that inflammation is associated with disease development and progression, and is predictive of poor outcomes, independent of traditional markers such as left ventricular ejection fraction or New York Heart Association functional class. Watch now
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