CardioBites Plus: Amyloidosis - Mechanism of Disease-CardioBites Plus: Amyloidosis

CardioBites Plus: Amyloidosis - Mechanism of Disease1

Video Transcription

Video Summary

The video discusses amyloidosis, focusing on its mechanism and implications, with insights from two cardiologists, Dr. Justin Grodin and Dr. Jobin Vaishnav. Amyloidosis involves the misfolding of proteins into amyloid fibrils, affecting various organs, notably the heart, leading to systemic dysfunction. Two main types, AL (immunoglobulin light chains) and ATTR (transthyretin), are highlighted, with ATTR being more common. The discussion covers genetic and lifestyle factors contributing to disease variability and onset age. Understanding these factors could guide treatment and lifestyle choices to manage amyloidosis effectively.

Keywords

amyloidosis

protein misfolding

ATTR

cardiologists

treatment strategies